Mission

Our goal is to understand, model, and recapitulate in vitro the instructive signals utilized by human embryos to pattern tissue-specific differentiation of pluripotent stem cells, and apply this knowledge towards the rational design of tissue engineered scaffolds and other regenerative therapeutic strategies. Currently, we primarily focus on generating tissues and therapies for the central nervous system.

Recent Publications

Knight GT, Sha J, Ashton RS (2015)
Chemical Communications, (in press)

Saraswathy M, Knight GT, Pilla S, Ashton RS, Gong S (2015)
Colloids and Surfaces B: Biointerfaces, 126: 590-97  

Fabricating Complex Culture Substrates Using Robotic Microcontact Printing (R-μCP) and Sequential Nucleophilic Substitution
Gavin T. Knight, Tyler Klann, Jason D. McNulty, Randolph Scott Ashton (2014)
JOVE (92), e52186

Micropattern width dependent sarcomere development in human ESC-derived cardiomyocytes
Salick M, Napiwocki BN, Sha J, Knight GT, Chindhy SA, Kamp TJ, Ashton RS, Crone WC (2014)
Biomaterials, 35(3): 4454-64

More Publications

  • Science Photo
  • Science Photo
  • Science Photo
  • Photo of Cardiomyocyte Bucky
  • Photo of Neural Rosette
  • Photo of Micropatterned Molecules
  • Photo showing E6 Method
  • Photo demonstrating a Reaction
  • Link to YouTube Video

Announcements

February 2015
Randolph Ashton named a 2015 Emerging Investigator by Chemical Communications, an RCS Journal. 


January 2015
Gavin Knight and Randolph Ashton collaborate with the Gong Lab to co-author an article on "Multifunctional drug nano carriers formed by cRGD-conjugated βCD-PAMAM-PEG for targeted cancer therapy" in Colloids and Surfaces B: Biointerfaces. 

Randolph Ashton selected as a faculty member of UW–Madison's Material Science Program and Neuroscience Training Program

The Ashton Group welcomes graduate students Brett Napiwocki and Julio Cesar Diaz to the SCBRM lab!