Our goal is to understand, model, and recapitulate in vitro the instructive signals utilized by human embryos to pattern tissue-specific differentiation of pluripotent stem cells, and apply this knowledge towards the rational design of tissue engineered scaffolds and other regenerative therapeutic strategies. Currently, we primarily focus on generating tissues and therapies for the central nervous system.

Recent Publications

ES Lippmann, MC Estevez-Silva, RS Ashton (2015)
Protocol Exchange [doi:10.1038/protex.2015.076]

Harkness. T., McNulty, J.D., Prestil, R., Seymour, S.K., Klann, T., Murrell, M., Ashton, R. S. and Saha, K. (2015)
Biotechnology Journal. doi: 10.1002/biot.201400756
ES Lippmann, CE Williams, DA Ruhl, MC Estevez-Silva, ER Chapman, JJ Coon, RS Ashton (2015)
Stem Cell Reports, 4(4): 632-44

Knight GT, Sha J, Ashton RS (2015)
Chemical Communications, 51(25): 5238-5241

  • Science Photo
  • Science Photo
  • Science Photo
  • Photo of Cardiomyocyte Bucky
  • Photo of Neural Rosette
  • Photo of Micropatterned Molecules
  • Photo showing E6 Method
  • Photo demonstrating a Reaction
  • Link to YouTube Video


September - December 2016
The Ashton Group welcomes Nikolai Fedorchak (Lab Manager/Research Specialist), Nisha Iyer (Postdoctoral Research Associate, from Prof. Sakiyama-Elbert lab at Washington University in St. Louis), and Andrew Baldys, Frank Seipel, Alexandra Doersch, and Stephanie Cuskey as new Undergraduate Research Assistants.

Randolph Ashton is awarded a "Creative Community Innovation Grant" from UW Madison's Division of Diversity, Equity & Educational Achievement to help further advance the Biomedical Engineering Department's Diversity Outreach Program.

Congratulations to Gavin Knight and Carlos Marti-Figueroa for successful research talks at the Biomedical Engineering Society's 2016 Annual Meeting.

Congratulations to Brady Lundin for a successful poster presentation at the Biomedical Engineering Society's 2016 Annual Meeting.

Brady Lundin & Akshitha Sreeram begin their research projects as 2016 Hilldale Undergraduate Research Scholars!