University of Wisconsin–Madison

Announcements

September 2017
Congratulations to Principal Investigator Randolph Ashton for receiving a NIH R33 award from the National Institute of Neurological Disorders and Stroke for $779,184 in support of our project titled “High-throughput Modeling of ALS Using iPSC-Derived Neural Tube Microarrays.”

The Ashton Group at UW-Madison in collaboration with other intra-University research groups, the University of Georgia, and the University of Puerto Rico-Mayaguez Campus, were awarded a $20 million NSF grant to start an Engineering Research Center for Cell Manufacturing Technologies.

The Ashton Group also welcomes a new Undergraduate Research Assistant Siddhant Jain.

August 2017
Dr. Randolph Ashton hosts the 2017 Advanced Biomanufacturing Conference at the Wisconsin Institute for Discovery. Click here to view pictures from this years event.

July 2017
Congratulations to Dr. Nisha Iyer for her acceptance to the 2017 NextProf Fall Engineering Workshop at the University of Michigan in Ann Arbor (Sept. 26-29, 2017).

June 2017
Congratulations to Maria Estevez-Silva for her presentation of “Towards an In Vitro Model of the Human Posterior CNS” at ISSCR 2017 in Boston, MA. Congratulations to Alireza Aghayee and Kristen Lemke for publishing “Deriving, Regenerating, and Engineering CNS Tissues using Human Pluripotent Stem Cells” in the journal Current Opinion in Biotechnology.

May 2017
Congratulations new graduates: Gavin Knight (PhD, BME), Maria Estevez-Silva (MS, BME), Akshitha Sreeram (BS, Neurobiology), Brady Lundin (BS, BME), and Kristen Lemke (BS, Chem Engineering)!

April 2017
Congratulations to graduate students Maria Estevez Silva, Carlos Marti-Figueroa, Gavin Knight, Brett Napiwocki, and undergraduate Akshitha Sreeram for presenting their research efforts at the 2017 Stem Cell Symposium and the 2017 UW Madison Undergraduate Research Symposium (see pics here at bottom of Group Activities page).

March 2017
Congratulations to Carlos Marti-Figueroa for his research efforts and recent publication titled “The Case for Applying Tissue Engineering Methodologies to Instruct Human Organoid Morphogenesis” in the Journal Acta Biomaterialia.

February 2017
Randolph Ashton was awarded a NSF CAREER Award February 23rd, 2017. The Faculty Early Career Development (CAREER) Program is a Foundation-wide activity that offers the National Science Foundation’s most prestigious awards in support of early-career faculty who have the potential to serve as academic role models in research and education and to lead advances in the mission of their department or organization. Activities pursued by early-career faculty should build a firm foundation for a lifetime of leadership in integrating education and research (click here to view Proposal Summary details).

September – December 2016
The Ashton Group welcomes Nikolai Fedorchak (Lab Manager/Research Specialist), Nisha Iyer (Postdoctoral Research Associate, from Prof. Sakiyama-Elbert lab at Washington University in St. Louis), and Andrew Baldys, Frank Seipel, Alexandra Doersch, and Stephanie Cuskey as new Undergraduate Research Assistants.

Randolph Ashton is awarded a “Creative Community Innovation Grant” from UW Madison’s Division of Diversity, Equity & Educational Achievement to help further advance the Biomedical Engineering Department’s Diversity Outreach Program.

Congratulations to Gavin Knight and Carlos Marti-Figueroa for successful research talks at the Biomedical Engineering Society’s 2016 Annual Meeting.

Congratulations to Brady Lundin for a successful poster presentation at the Biomedical Engineering Society’s 2016 Annual Meeting.

Brady Lundin & Akshitha  Sreeram begin their research projects as 2016 Hilldale Undergraduate Research Scholars!

August – November 2015

The Ashton lab publishes a detailed HOX patterning protocol on Nature’s Protocol Exchange.

Gavin Knight delivers a talk on “Micropatterned Substrates for Spatiotemporal Control of Neural Tissue Morphogenesis” at the 2015 Biomedical Engineering Society Annual Meeting (October)

Randolph Ashton delivers a talk on “Region-specific Cells and Tissue Models for Hindbrain & Spinal Cord Regenerative Medicine” at the Waisman Center and Allen Institute Neuroscience Symposium (16 October)

Randolph Ashton delivers a webinar on “Brain Models for Analysis of Pathways (BRAIN MAPS)” at the Environmental Protection Agency’s National Center for Computational Toxicology, Virtual Tissue Models Meeting  (14 October)

Randolph Ashton delivers a talk on “Engineering Hindbrain and Spinal Cord Tissues for Toxicology and Regenerative Medicine” at Hampton University’s 2nd Annual Engineering Alumni Research Symposium (October)

The Ashton Group welcomes Katherine Jeffris and Maria Estevez-Silva as new graduate students to the SCBRM lab.

The Ashton Group welcomes Kristen Lemke to the group as a new undergraduate research assistant in the SCBRM lab.

 

June – July 2015
Congratulations to Gavin T. Knight for successfully completing his Ph.D. candidacy exam!

In collaboration with Prof. Krishanu Saha and Michael Murrell, Ty Harkness and Jason McNulty publish an article on “High-content imaging with micropatterned multiwell plates reveals influence of cell geometry and cytoskeleton on chromatin dynamics” in Biotechnology Journal.

Randolph Ashton delivers a talk on “From Niche to Tissue: Engineering Neural Stem Cell Derivation, Differentiation, and Tissue Morphogenesis” at the 2015 Gordon Research Conference on Biomaterials and Tissue Engineering in Girona, Spain.

Randolph Ashton delivers a talk on “Engineering Region-specific Cells and Organotypic Tissues of the Central Nervous System” at the International Society for Stem Cell Research’s 2015 Annual Meeting in Stockholm, Sweden.

March – April 2015

The U.S. Environmental Protection Agency awards a team of research labs, lead by Prof. William Murphy and including the Ashton lab, $6 million to establish the Human Models for Analysis of Pathways (H-MAPs) Center at UW-Madison. The Ashton lab will use $1.18 million of that funding to develop novel in vitro models of the human central nervous system. ( UW–Madison announcementWisconsin Institute for Discovery announcement)

Ethan Lippmann publishes an article on “Deterministic HOX patterning in human pluripotent stem cell-derived neuroectoderm” in Stem Cell Reports.

Congratulations to Ethan Lippmann for his acceptance of an Assistant Professorship in the Chemical and Biomolecular Engineering Department at Vanderbilt University!

Congratulations to Ethan Lippmann for presenting a winning poster at the 10th Annual Wisconsin Stem Cell Symposium (Madison, WI)!

The Ashton Group welcomes Sayeed Alrieza Aghayee Meibody, a student in UW–Madison’s Material Science Program, to the SCBRM lab.

Congratulations to Alireza Aghayee Meibody for being selected as a ‘2015 Honored Instructor’ by the UW-Madison Housing Academic Initiatives: his students nominated him for making a meaningful impact on their education!

Congratulations to Jason McNulty for successfully completing his Ph.D. candidacy exam!

February 2015

Randolph Ashton named a 2015 Emerging Investigator by Chemical Communications, an RSC Journal.

Gavin Knight and Jin Sha publish an article on “Micropatterned, clickable culture substrates enable in situspatiotemporal control of human PSC-derived neural tissue morphology” in Chemical Communications.

January 2015

Gavin Knight and Randolph Ashton collaborate with the Gong Lab to co-author an article on “Multifunctional drug nano carriers formed by cRGD-conjugated βCD-PAMAM-PEG for targeted cancer therapy” in Colloids and Surfaces B: Biointerfaces.

Randolph Ashton selected as a faculty member of UW–Madison’s Material Science Program and Neuroscience Training Program.

The Ashton Group welcomes graduate students Brett Napiwocki and Julio Cesar Diaz to the SCBRM lab!

December 2014

Randolph Ashton delivers a talk on “Regional Specification of Hindbrain and Spinal Cord Neural Stem Cells derived from Human Pluripotent Stem Cells” at the Tissue Engineering and Regenerative Medicine International Society’s 2014 Annual Conference and Exposition (TERMIS-Americas).

November 2014

Dr. Ethan Lippmann delivers a talk on “Precision HOX Patterning in a Human Pluripotent Stem Cell Model of Posterior Neural Development” at the American Institute of Chemical Engineers’ 2014 Annual Meeting.

October 2014

Gavin Knight and Tyler Klann publish an article on “Fabricating Complex Culture Substrates Using Robotic Microcontact Printing (R-µCP) and Sequential Nucleophilic Substitution” in the Journal of Visualized Experiments (JOVE).

Dr. Ethan Lippmann presents a poster on “Deterministic HOX Patterning in Human Pluripotent Stem Cell-derived Posterior Neuroectoderm” at the Biomedical Engineering Society’s 2014 Annual Meeting.

Jason McNulty delivers a talk on “Robotic Microcontact Printing (R-µCP)” at the Biomedical Engineering Society’s 2014 Annual Meeting.

Randolph Ashton delivers an invited lecture entitled, “Engineering Next Generation CNS Tissue Models” at the American Chemical Society’s River Rock Regional Section Meeting at Rockford University (Rockford, IL).

September 2014

Congratulations to Gavin Knight for winning a $1000 travel grant for his winning poster, “Spatiotemporal control of neural stem cell adhesion and migration on RGD-modified PEG brushes”, at the 2014 UW Madison SCRMC Fall Conference.

Congratulations to Jason McNulty for successfully completing his PhD Qualifier examinations.

The Ashton lab would like to welcome Akshitha Sreeram, Brady Lundin, and Joshua Plantz to the group as new undergraduate research assistants.

August 2014
Congratulation to Professor Gordon Mitchell (co-PI) and Assistant Professor Randolph Ashton (co-PI) for receiving an ICTR Basic and Clinical Research Award on “Phrenic Motor Neuron Derivation and Transplantation” for $50,000. See announcement in the latest ICTR Newsletter.

Congratulations to Assistant Professor Randolph Ashton (PI) and Professor David Beebe (Co-I) for receiving a NIH R21 award from the National Institutes of Neurological Disorders and Stroke for $348,422.
Randolph Ashton selected to present a seminar entitled, “Engineering next-generation CNS tissue models” at UW Madison’s Stem Cell and Regenerative Medicine Center’s Fall Conference on September 12th, 2014 in the WID-Deluca Forum.
Ethan Lippmann and Jason McNulty selected to present talks at the Biomedical Engineering Society’s 2014 Annual Meeting in San Antonio, TX on October 22-25, 2014.
Congratulations to Assistant Professors Randolph Ashton (PI) and Krishanu Saha (Co-I) for receiving a Burroughs Welcome Fund Innovation in Regulatory Sciences Award for $500,000.”