University of Wisconsin–Madison

Engineering Tissue Morphogenesis

Engineering Tissue Morphogenesis
Engineering Tissue Morphogenesis

Spatiotemporal control of tissue morphology in standard cell culture is not longer a limitation! Using Robotic microcontact printing (R-µCP) and copper-free click chemistry, we have engineered culture substrates that can impose an initial, microscale tissue morphology to your cell culture, and at will, the tissue can be allowed to grow to a secondary morphology by simple supplementation of the cell culture media. Furthermore, the engineering culture substrates are chemically defined to enable designer, biospecific interaction between your cells and the substrate. In the associated Chemical Communications publication, we demonstrate the use of this engineered culture platform to control the morphogenesis of neural tissues derived from human pluripotent stem cells. If you desire to use such substrates in coverslip or standard 6-well plate format, please use the ‘Materials Request Form‘ under the ‘Resources’ header to request a consultation.